The Kidney and Its Main Blood Vessels
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As kidney failure progresses, some of the following symptoms may develop:
- Loss of appetite
- Nausea and vomiting
- Weight loss
- Itchy skin
- Trouble concentrating
- Swelling throughout the body
- Low urine output
- Generalized weakness
- Multiple bruises
- Numbness and tingling in the extremities
- Decreased desire for sexual activity
- Menstrual irregularities
- Muscle cramps and twitches
- Shortness of breath
- Chest pain
- Weak, brittle bones
- Yellowish-brownish skin tone
- Frequent hiccups
If kidney failure is untreated, the waste products and fluid that build up can result in:
Chronic kidney disease. EBSCO DynaMed website. Available at:
http://www.ebscohost.com/dynamed. Updated April 22, 2013. Accessed July 2, 2013.
End-stage renal disease. National Institute of Diabetes & Digestive & Kidney Diseases website. Available at:
Updated September 15, 2010. Accessed July 2, 2013.
Yu, HT. Progression of chronic renal failure.
Arch Int Med. 2003;163:1417-1429.
Last reviewed July 2013 by Adrienne Carmack, MD; Michael Woods, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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