WEDNESDAY, June 2 (HealthDay News) -- Tumor size among prostate
cancer patients appears to be linked to patient weight, with
heavier men having larger tumors, a new study reveals.
The finding stems from work involving more than 3,300 prostate
cancer patients with an average age of 60 who underwent surgery
between 2001 and 2007 to remove a malignant prostate gland and
surrounding tissue.
"As the patient's body mass index [BMI] increased, the tumor volume increased synchronously," Dr. Nilesh Patil, from the department of radiology at the Henry Ford Hospital's Vattikuti Urology Institute in Detroit, said in a news release. "Based on our results, we believe having a larger percentage of tumor volume may be contributing to the aggressive nature of the disease in men with a higher BMI."
BMI is a measurement of body fat that takes into account a
person's weight and height. In the study, BMI scores ranged from
24.9 or less for normal to underweight individuals, to 40 or higher
for morbidly obese individuals, the team noted.
Patil's team is slated to present the findings Wednesday in San
Francisco at the American Urology Association annual meeting.
The authors noted that prior research had already established
that aggressive prostate cancer was linked to having a higher
BMI.
To explore whether or not the cancer-BMI association translated
into bigger tumor size, the research team weighed and compared
tumors that had been removed from the patients.
The authors found that in every BMI category -- underweight,
normal, overweight, obese and morbidly obese -- tumor size
correlated directly with patient weight, with lower-weight patients
having smaller tumors and higher-weight patients having larger
tumors.
More information
For more on prostate cancer, visit the
U.S. National Cancer Institute.