THURSDAY, June 10 (HealthDay News) -- A simple eye test may one
day help diagnose multiple sclerosis in its earliest stages and
enable researchers to assess the effectiveness of treatments,
according to a new study.
The test -- optical coherence tomography (OCT) -- measures
thinning of the retina in people with MS, said researchers at UT
Southwestern Medical Center in Dallas.
"This technique has the potential to provide a powerful and reliable assessment strategy to measure structural changes in the central nervous system," study co-senior author Dr. Elliot Frohman, professor of neurology and ophthalmology and director of the Multiple Sclerosis Clinical Center at UT Southwestern, said in a medical center news release.
The test may not only be used for diagnostic purposes, but in
clinical trials "to monitor whether potential treatments can
prevent deterioration or restore nerve function," Frohman
added.
He and his colleagues used OCT to track retinal thinning in 299
MS patients for between six months and 4.5 years. They found
significant retinal thinning and a corresponding decrease in visual
sharpness during the patient monitoring.
OCT is reliable, easy to use, painless and sensitive to retinal
changes over time, the researchers concluded.
"An ophthalmologist might someday be able to use OCT to identify retinal thinning during a routine eye exam and consider MS as a prime diagnosis," Frohman said. "However, this prospect is a long way off."
The study appears in the June issue of the journal
Annals of Neurology. The research was a joint project with the University of Pennsylvania School of Medicine, John Hopkins University School of Medicine, and the University of Alabama at Birmingham.
More information
The U.S. National Institute of Neurological Disorders and Stroke
has more about
multiple sclerosis.