THURSDAY, July 8 (HealthDay News) -- A person's heart beat may
offer insight into their future kidney health, a new study
A high resting heart rate and low beat-to-beat heart rate
variability were noted in study patients with an increased risk for
kidney disease, according to a report released online July 8 in
advance of publication in an upcoming print issue of the
Journal of the American Society of Nephrology.
The finding suggests that dysfunction of the autonomic nervous
system -- which regulates involuntary body functions such as heart
rate, blood pressure, temperature and stress response -- may be a
marker for late development of certain types of kidney disease,
explained Dr. Daniel Brotman of Johns Hopkins University School of
Medicine and colleagues, in a news release from the American
Society of Nephrology.
Previous studies have suggested a link between autonomic nervous
system dysfunction (dysautonomia) and chronic kidney disease and
Brotman's team analyzed heart and kidney data from 13,241 U.S.
adults, aged 45 to 64, enrolled in a long-term study of
atherosclerosis risk. In general, a low resting heart rate and
greater beat-to-beat variability in heart rate indicate a healthy
autonomic nervous system and good cardiovascular health.
The researchers found that people with a high resting heart rate
had a twofold increased risk of developing kidney failure years
later, and those with a lower beat-to-beat variability in heart
rate had a 1.5-times increased risk.
Brotman and colleagues noted that this does not prove a
cause-and-effect relationship, but they speculated that problems in
the autonomic nervous system may damage blood vessels in and around
"We hope our findings will encourage further research to better define the putative role of the autonomic nervous system in precipitating and exacerbating renal [kidney] disease in humans," the authors wrote. "This, in turn, may ultimately lead to novel therapeutic approaches once the mechanisms for our findings are better characterized."
The National Kidney Disease Education Program offers
tips for keeping your kidney healthy.