THURSDAY, July 15 (HealthDay News) -- Vascular disease, which
affects blood flow in brain vessels, appears to be a common cause
of dementia in some people with diabetes, new study findings
suggest.
That's in contrast to dementia in people without diabetes, which
the researchers say is more likely to be linked to the brain plaque
deposits commonly seen in people with Alzheimer's disease.
The findings come from researchers at the Mayo Clinic's Florida
campus and the University of California, San Francisco, who
compared the ratios of two different types of amyloid beta proteins
in blood samples from 211 people with dementia and 403 others
without dementia.
"This helps in understanding diabetes and dementia. It suggests that the vascular dementia seen in diabetics, which appears to be related to small blood vessel disease and strokes, can potentially be averted if development of diabetes is prevented," neurologist Dr. Neill Graff-Radford said in a Mayo Clinic news release.
The study findings were slated for presentation July 14 at the
Alzheimer's Association International Conference on Alzheimer's
Disease meeting, in Hawaii.
The findings support previous autopsy studies on people with
diabetes and dementia, which found vascular abnormalities were
related to dementia but not to the plaques and tangles
characteristic of Alzheimer's disease, the authors noted in the
news release.
More information
The U.S. National Institute of Neurological Disorders and Stroke
has more about
dementia.