FRIDAY, July 16 (HealthDay News) -- Getting tested for
inflammatory bowel disease through an endoscopy isn't a pleasant
experience, but a new review of existing research suggests that a
simple stool test may help doctors figure out who needs the more
extensive screening.
Inflammatory bowel disease refers to a number of conditions --
including Crohn's disease and ulcerative colitis -- that can cause
abdominal pain, diarrhea and bleeding (the disease is sometimes
confused with irritable bowel syndrome, which is a different
condition.)
Doctors look for signs of disease through endoscopies, which are
procedures that require patients to allow a tube to be passed into
their digestive system from the rectum.
In the new review, published online July 16 in
BMJ, researchers sought to discover whether a test of proteins in the stool could help doctors discover whether an endoscopy is necessary.
The researchers, from University Medical Center Groningen in the
Netherlands, analyzed six studies in a total of 670 adults and
seven studies in a total of 371 children. They found that, overall,
the protein screening reduced the number of endoscopies by
two-thirds in adults and about one-third in children. But it also
delayed diagnosis in 6 percent to 8 percent of the patients.
The stool test "is a useful screening tool for identifying
patients who are most likely to need endoscopy for suspected
inflammatory bowel disease," concluded Dr. Patrick van Rheenen, a
pediatric gastroenterologist at University Medical Center
Groningen, and colleagues in their report.
Dr. David A. Schwartz, a gastroenterologist who was not involved
in the review, said the findings have the potential to change the
way doctors screen patients. "If this strategy is borne out by
future studies, and we get a rapid test that can be done in the
office, this should be a nice addition to our diagnostic tools,"
said Schwartz, director of the Inflammatory Bowel Disease Center at
Vanderbilt University.
In the big picture, Schwartz said, the findings are encouraging
because they show medicine is moving closer to a way to check for
inflammatory bowel disease without having to rely on an invasive
test.
More information
The American Academy of Family Physicians has more about
inflammatory bowel disease.