THURSDAY, July 22 (HealthDay News) -- In a new study that looked
at the use of nitric oxide in premature infants, researchers found
that lung function didn't improve in babies who were not black,
although one expert said the treatment may help some infants.
Laboratory tests have suggested that nitric oxide may be able to
help stimulate lung growth in premature newborns, who often can't
breathe properly because their lungs aren't fully developed,
explained Dr. Steven H. Abman, director of the Pediatric Heart Lung
Center at University of Colorado School of Medicine and The
Children's Hospital. Abman was not involved in the new study but is
familiar with the findings.
Studies in babies haven't consistently shown that nitric oxide
treatment helps babies as a whole, Abman noted. "The questions are
whether we're giving too little nitric oxide, or if we're picking
the wrong babies to treat," he said.
In the new study by Jean-Christophe Mercier, of the University
of Paris, and an international research team, doctors gave either
nitric oxide gas or a placebo to 800 preterm infants who were born
between 24 weeks and just under 29 weeks of gestation. The babies
had mild to moderate lung problems and were treated for seven to 21
days.
The nitric oxide treatment didn't appear to help the babies
avoid future lung problems and brain damage, the researchers found.
The results suggest that "such a preventive treatment strategy is
unsuccessful," they wrote in the report, published online July 22
in
The Lancet.
However, the treatment seemed to be somewhat effective in black
babies, and other studies have shown they may be helped more than
others, the study authors noted.
Abman suggested that the babies in the study may have been too
healthy to need the treatment, and more research is needed.
Nitric oxide is found in mammals and should not be confused with
nitrous oxide, or "laughing gas," which is used as an
anesthetic.
More information
For more about
premature babies, try the U.S. National Library of Medicine.