TUESDAY, April 5 (HealthDay News) -- Extreme weight gain
increases breast cancer survivors' risk of cancer recurrence and
death, but moderate weight gain has no effect on outcomes, a new
Researchers analyzed data from 18,336 breast cancer survivors in
the United States and China, ages 20 to 83, whose weight was
assessed 18 to 48 months after diagnosis and compared with their
Extreme weight gain (10 percent or greater than pre-diagnosis
weight) occurred in 16 percent of the women. They were 14 percent
more likely to suffer a cancer recurrence than women whose weight
remained stable (within 5 percent of their pre-diagnosis
Among the women with extreme weight gain, 19.4 percent had a
body mass index (BMI) lower than 25, which is considered normal
weight, before their diagnosis of breast cancer. These women had a
25 percent increased risk of cancer death and also had an increased
risk of cancer recurrence.
The study is to be presented Tuesday at the annual meeting of
the American Association for Cancer Research, in Orlando, Fla.
Research presented at meetings is considered preliminary until it
is published in a peer-reviewed journal.
"Most women are not gaining a large amount of weight following breast cancer diagnosis. But our analysis of the pooled data showed an association with poorer outcomes overall for those who do," lead researcher Bette Caan, senior research scientist at the Kaiser Permanente Division of Research, said in an AACR news release.
Further research is needed to learn why extreme weight gain puts
breast cancer survivors at increased risk for worse outcomes, Caan
The U.S. National Cancer Institute has more about