TUESDAY, Sept. 20 (HealthDay News) -- People affected by
epilepsy are nearly eight times more likely than those without it
to develop schizophrenia, and those with schizophrenia are also six
times more likely to have epilepsy than people who are not
schizophrenic, a new study suggests.
Researchers in Taiwan say this two-way relationship between the
two conditions may be due to genetic, environmental or
After analyzing information on almost 5,200 patients with
schizophrenia and more than 11,500 patients with epilepsy and
controls matched for age and sex in both groups, researchers found
the prevalence of epilepsy was higher in the schizophrenia patient
group at about 7 per 1,000 person-years, compared to just over 1
per 1,000 among those not affected by schizophrenia.
Meanwhile the study, published in
Epilepsia, showed the prevalence of schizophrenia was about 3.5 per 1,000 person-years for patients with epilepsy, compared to about 0.5 among those without epilepsy. The researchers noted the incidence of schizophrenia was slightly higher among men with the disease than women.
"Our research results show a strong bidirectional relation between schizophrenia and epilepsy," said the study's lead author Dr. I-Ching Chou, an associate professor with China Medical University in Taichung, Taiwan, in a journal news release. "This relationship may be due to common pathogenesis in these diseases such as genetic susceptibility and environmental factors, but further investigation of the pathological mechanisms are needed."
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