MONDAY, Dec. 12 (HealthDay News) -- Breast cancer survivors can
experience memory and concentration problems several years after
treatment with radiation and/or chemotherapy, a new study says.
The findings suggest that there may be common and
treatment-specific ways that these cancer therapies impair cancer
survivors' mental abilities, according to Paul Jacobsen, of the
Moffitt Cancer Center and Research Institute in Tampa, Fla., and
colleagues.
The study included 62 breast cancer survivors treated with
chemotherapy plus radiation, 67 patients treated with radiation
only and 184 women with no history of cancer. The breast cancer
patients underwent neurological assessments six months and three
years after completing treatment.
The researchers found that chemotherapy can cause cognitive, or
thinking, problems that persist for three years after breast cancer
survivors finish treatment. This pattern of changes is often called
"chemo brain." They also found that patients who were treated with
radiation alone often had cognitive problems similar to those
treated with both radiation and chemotherapy.
There was no indication that hormonal therapy, such as
tamoxifen, caused cognitive problems.
The study was published online Dec. 12 in the journal
Cancer.
"These findings suggest that the problems some breast cancer survivors have with their mental abilities are not due just to the administration of chemotherapy," Jacobsen said in a journal news release.
"Our findings also provide a more complete picture of the impact of cancer treatment on mental abilities than studies that did not follow patients as long or look at mental abilities in breast cancer survivors who had not been treated with chemotherapy," he added.
More information
The American Cancer Society offers an overview of
chemotherapy-related cognitive problems commonly referred to as
chemo brain.