WEDNESDAY, March 21 (HealthDay News) -- Most sinus infections
are caused by viruses and should
not be treated with antibiotics, which target bacteria and
are useless against viruses, new expert guidelines state.
About 14 percent (one in seven) of people are diagnosed with a
sinus infection each year, and sinus infections remain the fifth
leading reason for an antibiotic prescriptions. However, between 90
percent and 98 percent of the infections are caused by viruses,
which are not affected by antibiotics, according to the Infectious
Diseases Society of America (IDSA), which released the new advisory
on Wednesday.
IDSA noted that the inappropriate overuse of antibiotics is
encouraging the development of tough-to-treat, drug-resistant
bacteria or "superbugs."
An inability to determine which germ is behind a particular case
of sinusitis often leads to inappropriate prescribing, one expert
said.
"There is no simple test that will easily and quickly determine whether a sinus infection is viral or bacterial, so many physicians prescribe antibiotics 'just in case,'" Dr. Anthony Chow, chair of the guidelines panel and professor emeritus of infectious diseases at the University of British Columbia, Vancouver, said in an IDSA news release.
"However, if the infection turns out to be viral -- as most are -- the antibiotics won't help and in fact can cause harm by increasing antibiotic resistance, exposing patients to drug side effects unnecessarily and adding cost," Chow noted.
Most sinus infections -- which can cause uncomfortable pressure
on either side of the nose and last for weeks -- develop during or
after a cold or other respiratory infection. But other factors,
such as allergens and environmental irritants, may play a role.
Experts agreed with the new guidelines.
The recommendations "recognize two common problems with previous
guidelines: bacterial rhinosinusitis is overdiagnosed and
antibiotic resistance among common sinus pathogens has increased
significantly," said Dr. Richard Lebowitz, an otolaryngologist at
NYU Langone Medical Center and associate professor at the NYU
School of Medicine, in New York City.
He believes the recommendations are an "improvement" on prior
guidelines, but there are also "potential pitfalls" if a diagnosis
isn't clear. "The gold standard [for diagnosis], and the only way
to avoid misdiagnosis and improper treatment, is with
endoscopy-based diagnosis and culture-directed antibiotic therapy,"
Lebowitz said.
Another expert noted that there is often "confusion" in
distinguishing viral from bacterial sinusitis, because symptoms are
often similar. Still, "most patients want some kind of treatment
when they go to the doctor," said Dr. Linda Dahl, an ear, nose and
throat specialist at Lenox Hill Hospital in New York City. "The new
guidelines establish updated recommendations for treating these
patients in the primary care setting," she said.
The IDSA guidelines also recommend treating the small fraction
of sinus infections caused by bacteria with
amoxicillin-clavulanate, rather than the current standard of care,
amoxicillin. This recommendation was made due to increases in
antibiotic resistance as well as the widespread use of pneumococcal
vaccines, which have altered the pattern of bacteria that cause
sinus infections, Chow explained.
The guidelines also recommend shorter antibiotic treatment times
(five to seven days) for adults with bacterial sinus
infections.
Patients with either bacterial or viral sinus infections should
avoid decongestants and antihistamines, IDSA added. They are not
helpful and could make symptoms worse, the IDSA team said. Nasal
steroids may help people with sinus infections who have a history
of allergies. Nasal irrigation using a sterile solution in the form
of spray, drops or liquid may help relieve some symptoms, according
to the guidelines.
Dahl said she found the guidelines, "very useful and in line
with the way I practice with a few exceptions." On the issue of
decongestants, she said, "I advocate for decongestants in relieving
symptoms and preventing viral infections from turning into
bacterial infections. The sinuses are literally holes in our skull
that produce mucus. If the lining of the sinuses becomes inflamed
the mucus cannot drain and can harbor bacterial growth. By keeping
the passages open (with decongestants and nasal sprays) the sinuses
can heal more quickly."
Other treatments might help some patients, Dahl added, including
"manual suctioning of the sinuses, topical antibiotics [in certain
cases], and anti-inflammatories such as fish oil that are quite
helpful and speed recovery. And most importantly, rest and good
sleeping habits."
More information
The U.S. National Institute of Allergy and Infectious Diseases
has more about
sinus infection.