MONDAY, Aug. 1 (HealthDay News) -- When women take a supplement
of the omega 3 fatty acid DHA during pregnancy, their babies have
fewer cold symptoms and shorter illnesses, new research
indicates.
At 1 month and 3 months of age, about 38 percent of babies
exposed to docosahexaenoic acid (DHA) in the womb experienced cold
symptoms, compared to about 45 percent of the babies whose mothers
were given a placebo supplement while they were pregnant.
"The data suggested that for most of the symptoms we looked at, duration of symptoms was less when mothers received DHA. And, in the case of colds, the probability of a cold was slightly less. The effects seemed to be strongest early on after birth," said study senior author Usha Ramakrishnan, an associate professor in the Hubert Department of Global Health at the Rollins School of Public Health at Emory University in Atlanta.
Ramakrishnan said it's probably too soon to recommend routine
use of DHA supplements for pregnant women, because the findings
weren't "dramatic." But, she added that the supplements did appear
to be safe for pregnant women to take.
Results of the study will be published online on Aug. 1, and are
scheduled to appear in the September issue of
Pediatrics. The research was funded by the U.S. National Institutes of Health and the March of Dimes Foundation.
Omega 3 fatty acids are a class of nutrients considered
essential for neural and retinal development during pregnancy. They
are often obtained through diet by eating fish. But, concerns about
mercury contamination in fish have led to recommendations that
advise pregnant women to limit their fish consumption. Pregnant
women are also advised to avoid certain fish, such as swordfish,
altogether.
Therefore, the current study looked at DHA supplements derived
from algae. Ramakrishnan said there are no concerns about mercury
contamination in DHA from algae.
More than 800 Mexican women were included in the study. Half
were randomly selected to be in the treatment group while the other
half received a daily placebo pill. The treatment group received
400 milligrams of DHA each day, beginning when they were between 18
and 22 weeks pregnant. Treatment continued at least until the birth
of the baby.
Ramakrishnan said Mexican women tend to be deficient in DHA,
much like many American women are.
The babies were assessed at 1, 3 and 6 months of age, and the
mothers completed questionnaires about their babies' health. To aid
their recall, the mothers were also asked to keep a diary,
recording any illness symptoms.
Babies in the DHA group had a 24 percent drop in the odds of
having a combination of cold symptoms at 1 month compared to babies
whose mothers were given a placebo. Also at 1 month, babies whose
mothers had gotten the DHA supplement had 26 percent shorter
duration of cough, 15 percent less time with phlegm and 30 percent
shorter duration of wheezing.
At 3 months, babies in the DHA group were also sick 14 percent
less time. And, at 6 months, the babies whose mothers had DHA had
shorter duration of fever, runny nose and breathing problems.
At times, however, babies in the DHA group experienced longer
duration of rashes and vomiting, the study authors noted.
Ramakrishnan said that it's likely that DHA boosts infants'
immune response.
Dr. Jennifer Wu, an obstetrician and gynecologist at Lenox Hill
Hospital in New York City, said, "We've been recommending DHA
intake in pregnant women for brain and nervous system development,
and this study suggests another good reason to take DHA."
Wu recommended that women who are thinking about becoming
pregnant should "start prenatal vitamins and DHA supplements about
three months before pregnancy and then continue them throughout the
pregnancy. If you're not taking them ahead of time, you may miss
out on proper nutrition," she added.
More information
Learn more about omega-3 fatty acids, including DHA, and infant
health from the
March of Dimes.