MONDAY, May 16 (HealthDay News) -- In men who've had their
prostate surgically removed due to prostate cancer, smoking seems
linked to a rise in blood levels of prostate specific antigen (PSA)
-- a measure of the risk of cancer recurrence.
So finds a new study slated to be presented Monday at the annual
meeting of the American Urological Association (AUA) in Washington,
The study included 321 smokers and 309 nonsmokers who underwent
radical prostatectomy (surgical removal of the prostate) between
1989 and 2005. Smokers had a higher volume and a greater volume of
high-grade cancer than nonsmokers, according to the Stanford
University School of Medicine researchers.
Smokers also tended to chart a steeper rise in their blood
levels of PSA, signaling a greater risk of "biochemical recurrence"
of prostate cancer. PSA levels rose approximately one percent per
pack-year smoked, the team found.
"These data indicate that smoking history could provide valuable insight and should be included in risk-assessment models for prostate cancer," study presenter Dr. Joseph C. Presti said in an AUA news release.
"The study also presents a strong message to men: quitting smoking now could impact your ability to survive prostate cancer later," he added.
The U.S. National Cancer Institute has more about