Research Publications
The Henry Low Heart Center is a major center for cardiovascular research.  It is different from other heart centers because it offers greater breadth of treatment options.  New clinical programs are derived from cutting edge research in novel areas.

1.     Bateman T, Heller GV, McGhie I, Friedman J, Case J, Bryngelson J, Hertenstein G, Moutray K, Reid K, Cullom SJ.  Diagnostic Accuracy of Rest/Stress ECG-gated Rubidium-82 Myocardial Perfusion PET:  Comparison with ECG-gated Tc-99m-Sestamibi SPECT.  J Nucl Cardiol 2006;12:24-33.


2.     Baghdasarian SB, Heller GV.  The role of myocardial perfusion imaging in the diagnosis of patients with coronary artery disease:  developments over the past year.  Curr Opin Cardiol 2005 20:369-374.


3.     Baghdasarian SB, Thompson PD.  How safe are very low LDL cholesterol levels? Nat Clin Pract Cardiovasc Med. 2006 Jun;3(6):306-7.


4.     Blanchard BE, Tsongalis GJ, Guidry MA, LaBelle LA, Poulin M, Taylor AL, Maresh CM, Devaney J, Thompson PD, Pescatello LS.  RAAS polymorphisms alter the acute blood pressure response to aerobic exercise among men with hypertension. Eur J Appl Physiol. 2006 May;97(1):26-33.


5.     Chyun DA, Melkus GD, Katten DM, Price WJ, Davey JA, Grey N, Heller GV, Wackers FJTh.  The Association of Psychological Factors, Physical Activity, Neuropathy, and Quality of Life in Type 2 Diabetes.  Biological Research for Nursing 2006, 7 (4):279-288.


6.     Clarkson PM, Kearns AK, Rouzier P, Rubin R, Thompson PD. Serum creatine kinase levels and renal function measures in exertional muscle damage. Med Sci Sports Exerc. 2006 pr;38(4):623-7.


7.     Cosio-Lima LM, Thompson PD, Reynolds KL, Headley SA, Winter CR, Manos T, Lagasse MA, Todorovich JR, Germain M. The acute effect of aerobic exercise on brachial artery endothelial function in renal transplant recipients. Prev Cardiol. 2006;9:211-4.


8.     Dale K, Coleman CI, Henyan N, Kluger J, White CM. Statins and Cancer.  JAMA 2006;295:74-80.


9.     Dornelas, E.A., Fischer, E.H., Stepnowski, R.R., Thompson, P.D. Urban ethnic minority women’s attendance at health clinic vs. church-based exercise programs.  Journal of Cross Cultural Gerontology.  (in press).


10.   Dornelas, E.A., Magnavita, J.J., Beazoglou, T., Fischer, E.H. Oncken, C., Lando, H., Greene, J., Barbagallo, J., Stepnowski, R., Gregonis, E.  (2006). Efficacy and cost-effectiveness of a clinic-based counseling intervention tested in an ethnically diverse sample of pregnant smokers.  Patient Education and Counseling, 64, 342-349.


11.   Dornelas, E.A., Patten, C., Fischer, E.H., Decker, P.A., Offord, K., Barbagallo, J., Pingree, S., Croghan, I., Ahluwalia, J.S.  (2005). Ethnic variation in socioenvironmental factors that influence adolescent smoking, Journal of Adolescent Health, 36 (3), 170-177.


12.   Dornelas, E.A.& Thompson, P.D. Smoking Cessation in Cardiac Patients.  Preventive Cardiology. (in press).


13.   Fischer, E.H., Dornelas, E.A., Malchodi, C., Oncken, C. (2006).  Credibility of Self Report for Pregnant Smokers.  Journal of Applied Social Psychology, 36, 2825-2833.


14.   Gillespie EL, Gryskiewicz A, White CM, Kluger J, Humphrey C, Horowitz S, Coleman CI. Effect of aprotinin on the frequency of postoperative atrial fibrillation or flutter. Am J Health-System Pharmacy 2005;62:1370-74.


15.   Gillespie EL, Perkerson KA, White CM, Kluger J, Coleman CI.  Effect of Aprotinin on the incidence of postoperative atrial fibrillation after cardiothoracic surgery.  American Journal of Health-System Pharmacy 2005;62:1370-4.


16.   Gillespie E, White CM, Kluger J, Rancourt JA, Gallagher R, Coleman CI.  Cost Effectiveness of Amiodarone for Prophylaxis of Atrial Fibrillation After Cardiothoracic Surgery.  Pharmacotherapy 2006;26:499-504.

17.   Gryskiewicz K, Gillespie E, White CM, Kluger J, Gallagher R, Coleman CI. Impact of Hispanic Ethnicity on the Likeliness of Developing Postoperative Atrial Fibrillation.  Connecticut Medicine 2006;70:77-80.


18.   Guidry MA, Blanchard BE, Thompson PD, Maresh CM, Seip RL, Taylor AL, Pescatello LS. The influence of short and long duration on the blood pressure response to an acute bout of dynamic exercise. Am Heart J. 2006 Jun;151(6):1322.e5-12.


19.   Henyan N, Gillespie EL, White CM, Kluger J, Coleman CI.  The impact of intravenous Magnesium on post-cardiothoracic surgery atrial fibrillation and length of hospital stay:  A Meta-Analysis.  Annals of Thoracic Surgery 2005; 80:2402-2406.


20.   Henyan N, White CM, Gillespie EL, Smith K, Coleman CI, Kluger J.  The Impact of Gender on Survival Amongst Patients With Implantable Cardioverter Defibrillators for Primary Prevention Against Sudden Cardiac Death.  Journal of Internal Medicine.  2006;260(5):467-73.


21.   Hubal MJ, Gordish-Dressman H, Thompson PD, Price TB, Hoffman EP, Angelopulos TJ, Gordon PM, Moyna NM, Pescatello LS, Visich PS, Zoeller RF, Seip RL, Clarkson PM. Variability in muscle size and strength gain after unilateral resistance training. Med Sci Sports Excer. 2005, 37 (6): 964-72.


22.   Iwai S, Cantillon DJ, Kim RJ, Markowitz SM, Mittal S, Stein KM, Shah BK, Yarlagadda RK, Cheung JW, Tan VR, Lerman BB. Right and left ventricular outflow tract tachycardias: evidence for a common electrophysiologic mechanism. J Cardiovasc Electrophysiol. 2006 Oct; 17(10):1052-8.


23.   Jurado J, Thompson, PD. Prevention of coronary artery disease in cancer patients. Pediatr Blood Cancer. 2005, 44 (7): 620-4.


24.   Juszczyk MA, Seip RL, Thompson PD. Decreasing LDL cholesterol and medication cost with every-other-day statin therapy. Prev Cardiol. 2005 Fall;8(4):197-9.


25.   Kalus J, White M, Caron M, Guertin D, McBride BF, Kluger J.  The Impact of Catecholamines on Defibrillation Threshold in Patients with Implanted Cardioverter Defibrillators.  Pacing Clinical Electrophysiol. 2005;28(11):1147-1156.


26.   Kalus JS, White CM, Caron MF, Guertin D, McBride BF, Kluger J.  The impact of elevations in catecholamine concentrations on defibrillation threshold in patients with implanted cardioverter defibrillators.  The Defibrillation Threshold Effects of Catecholamines Trial (DTECT).  Pace, 2005;28:1147-56.


27.   Kapetanopoulos A, Kluger J, Maron BJ, Thompson PD. The congenital long QT syndrome and implications for young athletes. Med Sci Sports Exerc. 2006 May;38(5):816-25.


28.   Kapetanopoulous A, Peckham G, Kiernan F, Clyne C, Kluger, J, Migeed MA. Implantation of a biventricular pacing and defibrillator device via a persistent left superior vena cava. J Cardiovasc Med  2006 7;430-433.


29.   Kasapis C, Thompson PD. The effects of physical activity on serum C-reactive protein and inflammatory markersl a systemic review. J AM Coll Cariol. 2005, 45 (10): 1563-9.


30.   Kimmelstiel CD, Clyne CA: Cardiology Techniques:  A case-based approach. Chapter in Electrophysiologic Testing, Kimmelstiel, Hendel, (eds). Springer Publishing Co. 2006.


31.   Leaf A, Albert C, Josephson M, Steinhaus D, Kluger J, Kang J, Cox B, Zhang H, Schoenfeld D.  Prevention of Fatal Arrhythmias in High-Risk Subjects by Fish Oil n-3 Fatty Acid Intake.  Circulation. 2005;112:2762-2768.


32.   Leon AS, Franklin BA, Costa, F, Balady G, Berra KA, Stewart KJ, Thompson PD, Williams MA, Lauer MS.  AHA Scientific Statement: Cardiac Rehabilitation and Secondary Prevention of Coronary Heart Disease.  Circulation. 2005;111:369-376.

33.   Lertsburapa K, Shah A, Clyne CA.  The Impact of Cardiac Resynchronization Therapy on Atrial Tachyarrhythmia Incidence In Congestive Heart Failure Patients.  Circulation, 2006, October, 114 (18): II-616.


34.   Levine BD, Thompson PD. Marathon maladies. N Engl J Med. 2005, 352 (15): 1516-8.


35.   Levine BD, Pelliccia A, Thompspn PD, Douglas PS, Fu Q, DiPaolo F, Kiernan F, Zasadil M. The cardiovascular evaluation of women athletes. Med Sci Sports Exerc. 2005, 37 (8): 1431-2.


36.   Lundbye JB, Thompson PD. Statin use in the metablolic syndrome. Curr Atheroscler Rep. 2005, (1):17-21.


37.   Maron BJ, Douglas, PS, Graham TP, Nishimura RA, Thompson PD. Task force 1: preparticipation screening and diagnosis of cardiovascular disease in athletes. J Am Coll Cariol. 2005, 45 (8): 1322-6.


38.   Morasco, B.J., Dornelas, E.A., Fischer, E.H., Oncken, C., Lando, H.  (2006).  Spontaneous Smoking Cessation during Pregnancy among Ethnic Minority Women: A Preliminary Investigation.  Addictive Behaviors, (31), 203-210.


39.   Madias JE, Song J, White CM, Kalus JS, Kluger J. Response of the ECG to short term diuresis in patients with heart failure. Annals of Noninvasive Electrocardiology, 2005; 62:288-96.


40.   McBride BF, Min B, Guertin D, Kluger J, Henyan N, Coleman CI, Silver B, White CM. An Evaulation of the Impact of Oral Magnesium Lactate on the Corrected QT Interval of Patients Receiving Sotalol or Dofetilide to Prevent Atrial or Ventricular Tachyarrhythmia Recurrence.  Annals of Noninvasive Electrocardiology 2006;11:163-9.


41.   McKenney JM, Davidson MH, Saponaro J, Thompson PD, Bays HE. Use of a treatment algorithm to achieve NCEP ATP III goals with atorvastatin. J Cardiovasc Pharmacol. 2005 Nov;46(5):594-9.


42.   Min B, Cios D, Kluger J, White CM.  The hemodynamic and electrocardiographic effect of bitter orange extract in healthy volunteers. Pharmacotherapy.  2005;25:1719-24.


43.   Min B, Kalus J, Kluger J, Guertin D, McBride BF, White CM. The impact of catecholamines in patients with or without beta-blockers on ventricular fibrillation cycle length and variability.  Annals of Noninvasive Electrocardiology, 2005;10:305-11.


44.   Min B, McBride BF, Ismali, Kardas MJ, Sinha V, Kluger J, White CM.  The hemodynamic effects of an Ephedra free multicomponent weight loss supplement in healthy volunteers.  American Journal of Health-System Pharmacy, 2005;62:1582-5.


45.   Min B, McBride BF, Kardas MJ, Ismali A. Sinha V, Kluger J, White, CM. Electrocardiographic effects of an Ephedra free multicomponent weight loss supplement in healthy volunteers.  Pharmacotherapy 2005;25:654-9.


46.   Min B, McBride BF, Kardas MJ, Ismali A, Sinha V, Kluger J, White CM.  Hemodynamic Impact of an Ephedra-Free Multicomponent Weight-Loss Supplement.  American Journal of Health Systems Pharm.


47.   Ouyang P, Tardif JC, Herrington DM, Stewart KJ, Thompson PD, Walsh MN, Bennett SK, Heldman AW, Tayback MA, Wang NY; for the Estrogen And Graft Atherosclerosis Research (EAGAR) investigators. Randomized trial of hormone therapy in women after coronary bypass surgery Evidence of differential effect of hormone therapy on angiographic progression of disease in saphenous vein grafts and native coronary arteries. Atherosclerosis. 2006 Jan 23.

48.   Papaioannou GI, Kasapis, C, Seip RL, Grey NJ, Katten D, Wackers FJ, Inzucchi SE, Engel S, Taylor A, Young LH, Chyun DA, Davey JA, Iskandrian AE, Ratner RE, Robinson EC, Carolan S, Heller GV.  Value of peripheral vascular endothelial function in the detection of relative myocardial ischemia in asymptomatic type 2 diabetic patients who underwent myocardial perfusion imaging.  J Nucl Cardiol 2006;13:362-8.


49.   Patel AA, White CM, Gillespie EL, Kluger J, Coleman CI.  Safety of Amiodarone in the Prevention of Postoperative Atrial Fibrillation:  A Meta-Analysis.  American Journal of Health System Pharmacists 2006;63:829-37.


50.   Patel MD, Thompson PD. Phytosterols and vascular disease. Atherosclerosis. 2006 May;186(1):12-9.


51.   Patten, C.A., Croghan, I.T., Meis, T.M., Decker, P.A., Pingree, S., Colligan, R.C., Dornelas, E.A., Offord, K.P., Boberg, E.W., Baumberger, R.K., Hurt, R.D., Gustafson, D.H. (2006).  Randomized clinical trial of an internet-based versus brief office intervention for adolescent smoking cessation.  Patient Education and Counseling, 64, 249-258.


52.   Patten, C.A., Decker, P.A., Dornelas, E.A., Barbagallo, J., Rock, E., Offord, K., Hurt, R., Pingree, S.  (in press).  Changes in readiness to quit and self-efficacy among adolescents receiving a brief office intervention for smoking cessation.  Archives of Pediatrics and Adolescent Medicine.


53.   Pelliccia A, Thompson PD. The genetics of left ventricular remodeling in competitive athletes.  J Cardiovasc Med (Hagerstown). 2006 Apr;7(4):267-70. Review.


54.   Perkerson K, Gillespie E, White CM, Kluger J, Takata H, Coleman CI.  The impact of prophylactic Amiodarone on length of stay and stroke after cardiothoracic surgery.  Pharmacotherapy 2005; 25:320-4.


55.   Pescatello LS, Kostek MA, Gordish-Dressman H, Thompson PD, Seip RL, Price TB, Angelopoulos TJ, Clarkson PM, Gordon PM, Moyna NM, Visich PS, Zoeller RF, Devaney JM, Hoffman EP. ACE ID genotype and the muscle strength and size response to unilateral resistance training. Med Sci Sports Exerc. 2006 Jun;38(6):1074-81.


56.   Roberts BH, Thompson PD.  Is there evidence for the evidence-based guidelines for cardiovascular disease prevention in women? Gend Med. 2006 Mar;3(1):5-12. No abstract available.


57.   Ruano G, Thompson PD, Windemuth A, Smith A, Kocherla M, Holford TR, Seip R, Wu AH.  Physiogenomic analysis links serum creatine kinase activities during statin therapy to vascular smooth muscle homeostasis. Pharmacogenomics. 2005 Dec;6(8):865-72.


58.   Ruano G, Seip RL, Windemuth A, Zollner S, Tsongalis GJ, Ordovas J, Otvos J, Bilbie C, Miles M, Zoeller R, Visich P, Gordon P, Angelopoulos TJ, Pescatello L, Moyna N, Thompson PD. Apolipoprotein A1 genotype affects the change in high density lipoprotein cholesterol subfractions with exercise training. Atherosclerosis. 2006 Mar;185(1):65-9.


59.   Navare SM, Katten D, Johnson LJ, Mather JF, Fowler MS, Ahlberg AW, Miele N, Heller G.  Risk Stratification with ECG-gated Dobutamine Stress Technetium-99mSestamibi Single Photon Emission Tomographic Imaging: Value of heart rate response and assessment of LV function.  JACC 2006;47:781-8.


60.   Sander S, Coleman CI, Gillespie EL, Kluger J, White CM. Comparison of the Efficacy and Safety of Urokinase and Alteplase for Peripheral Arterial Occlusion:  A Meta-Analysis.  Pharmacotherapy 2006;26:51-60.


61.   Seip RL, Otvos J, Bilbie C, Tsongalis GJ, Miles M, Zoeller R, Visich P, Gordon P, Angelopoulos TJ, Pescatello L, Moyna N, Thompson PD. The effect of apolipoprotein E genotype on serum lipoprotein particle response to exercise. Atherosclerosis. 2006 Sep;188(1):126-33.

62.   Shaw LJ, Heller GV, Casperson P, Miranda-Peats R, Slomka P, Friedman J, Hayes SW, Schwartz R, Weintraub WS, Maron DJ, Dada M, King S, Teo K, Hartigan P, Boden WE, O’Rourke RA, Berman DS.  Gated myocardial perfusion single photon emission computed tomography in the clinical outcomes utilizing revascularization and aggressive drug evaluation (COURAGE) trial, Veterans Administration Cooperative study no. 424.  J Nucl Cardiol 2006;13:685-98.


63.   Steinmark, A., Dornelas, E.A. and Fischer, E. (2006).  Determinants and barriers to participation in an Internet-based recovery program for cardiac patients.  Journal of Clinical Psychology in Medical Settings, 13(4), 353-357.


64.   Syme AN, Blanchard BE, Guidry MA, Taylor AW, Vanheest JL, Hasson S, Thompson PD, Pescatello LS. Peak systolic blood pressure on a graded maximal exercise test and the blood pressure response to an acute bout of submaximal exercise. Am J Cardiol. 2006;98:938-43.


65.   Thompsen J, Thompson PD. A systematic review of LDL apheresis in the treatment of cardiovascular disease. Atherosclerosis. 2006 Mar 16.


66.   Thompson PD.  Exercise prescription and proscription for patients with coronary artery disease. Circulation. 2005 Oct 11;112(15):2354-63.


67.   Thompson PD, Balady GJ, Chaitman BR, Clark LT, Levine BD, Myerburg RJ. Task Force 6: coronary artery disease. J. AM Coll Cardiol. 2005, 45 (8): 1348-53.


68.   Thompson PD, Clarkson PM, Rosenson RS; The National Lipid Association Statin Safety Task Force Muscle Safety Expert Panel. An assessment of statin safety by muscle experts. Am J Cardiol. 2006 Apr 17;97(8A):69C-76C.


69.   Thompson PD, Kiernan F.  Prevention of Heart Disease in Female Athletes.  Med. Sci. Sports. Exerc. 2005;37(9):1440-1443.


70.   Thompson PD, Tsongalis GJ, Ordovas JM, Seip RL, Bilbie C, Miles M, Zoeller R, Visich P, Gordon P, Angelopoulos TJ, Pescatello L, Moyna N. Angiotensin-converting enzyme genotype and adherence to aerobic exercise training. Prev Cardiol. 2006 Winter;9(1):21-4.


71.   Thompson PD, Tsongalis GJ, Ordovas JM, Seip RL, Bilbie C, Miles M, Zoeller R, Visich P, Gordon P, Angelopoulos TJ, Pescatello L, Moyna N. Angiotensin-converting enzyme genotype and adherence to aerobic exercise training. Prev Cardiol. 2006, 9(1):21-4.


72.   Thompson RC, Heller GV, Johnson LL, Case JA, Cullom SJ, Garcia EV, Jones PG, Moutray KL, Bateman TM.  Value of attenuation correction on ECG-gated SPECT myocardial perfusion imaging related to body mass index.  J Nucl Cardiol 2005;12:195-202.


73.   Urso ML, Scrimgeour AG, Chen YW, Thompson PD, Clarkson PM. Analysis of Human Skeletal Muscle after 48h Immobilization Reveals Alterations in mRNA and Protein for Extracellular Matrix Components. J Appl Physiol. 2006 Jun 8.


74.   Yarlagadda RK, Iwai S, Stein KM, Markowitz SM, Shah BK, Cheung JW, Tan V, Lerman BB, Mittal S. Reversal of cardiomyopathy in patients with repetitive monomorphic ventricular ectopy originating from the right ventricular outflow tract. Circulation. 2005 ;112(8):1092-7.